Contact
- Drug Discovery
- Integrated Drug Discovery
- Bioscience
- Ion Channel Screening
- Cell Line Generation
- Assay Development
- Screening
- Cell Based Assays
- Biochemical Assays
- Biophysical Characterisation
- Surface Plasmon Resonance (SPR)
- Fluorescent Thermal Shift Assays (FTSA)
- Nuclear Magnetic Resonance (NMR)
- Flow Induced Dispersion Analysis (FIDA)
- Protein Mass Spectrometry
- X-Ray Crystallography (XRC)
- Isothermal Titration Calorimetry (ITC)
- Microscale Thermophoresis (MST)
- Dynamic Light Scattering (DLS)
- Biomarker Discovery
- Primary Tissues
- Protein Science and Structural Biology
- Chemistry
- Computer Aided Drug Design (CADD)
- DMPK
- In Vivo Pharmacology
- Form and Formulation
Contact
Primary Tissues
Our scientists are able to accelerate your drug discovery programme by designing custom cellular assays using primary tissues. These assays represent more biologically-relevant systems than immortalised cell models and allow the generation of (patho)physiologically-relevant data for your novel compounds.
Sygnature is able to source various animal and human primary tissues, as well as healthy and diseased tissue from our established links with preferred commercial vendors, our collaboration with a local biobank and through our in-house Blood Donor Panel. These cells can be further processed within our Human Tissue Authority (HTA)-licensed laboratories for use in Bespoke in vitro Assays to support your drug discovery project.
Contact
- Drug Discovery
- Integrated Drug Discovery
- Bioscience
- Ion Channel Screening
- Cell Line Generation
- Assay Development
- Screening
- Cell Based Assays
- Biochemical Assays
- Biophysical Characterisation
- Surface Plasmon Resonance (SPR)
- Fluorescent Thermal Shift Assays (FTSA)
- Nuclear Magnetic Resonance (NMR)
- Flow Induced Dispersion Analysis (FIDA)
- Protein Mass Spectrometry
- X-Ray Crystallography (XRC)
- Isothermal Titration Calorimetry (ITC)
- Microscale Thermophoresis (MST)
- Dynamic Light Scattering (DLS)
- Biomarker Discovery
- Primary Tissues
- Protein Science and Structural Biology
- Chemistry
- Computer Aided Drug Design (CADD)
- DMPK
- In Vivo Pharmacology
- Form and Formulation