Building a modern screening library and infrastructure
Many organisations have inherited a legacy library and screening infrastructure which in some cases has been tweaked to reflect modern thinking on lead-like properties and toxicity liabilities or improved informatics. At Sygnature we have been fortunate to be able to start with a clean slate and choose informatics and automation systems and select library compounds to provide a high diversity, high fidelity screening capability. Here we present the key components of our latest addition to our hit identification capabilities.